History of the Mole

History of the Mole

  Amadeo Avogadro


The number of objects in one mole, that is, 6.02 x 1023, is commonly referred to as Avogadro's number. Amadeo Avogadro was an Italian physics professor who proposed in 1811 that equal volumes of different gases at the same temperature contain equal numbers of molecules. About fifty years later, an Italian scientist named Stanislao Cannizzaro used Avogadro's hypothesis to develop a set of atomic weights for the known elements by comparing the masses of equal volumes of gas. Building on this work, an Austrian high school teacher named Johann Josef Loschmidt calculated the size of a molecule of air in 1865, and thus developed an estimate for the number of molecules in a given volume of air. While these early estimates have since been refined, they led to the concept of the mole - that is, the theory that in a defined mass of an element (its atomic weight) there is a precise number of atoms: Avogadro's number.

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